What is gestational trophoblastic disease?

Gestational trophoblastic disease (GTD) is a group of rare diseases in which abnormal trophoblast cells grow inside the uterus after conception. In gestational trophoblastic disease (GTD), a tumor develops inside the uterus from tissue that forms after conception (the joining of sperm and egg).

Is gestational trophoblastic disease the same as molar pregnancy?

A molar pregnancy happens when the fertilisation of the egg by the sperm goes wrong. This leads to the growth of abnormal cells or clusters of water filled sacs inside the womb. This condition is one of a group of conditions known as gestational trophoblastic disease (GTDs).

What is H mole in pregnancy?

Hydatidiform mole (HM) is a rare mass or growth that forms inside the womb (uterus) at the beginning of a pregnancy. It is a type of gestational trophoblastic disease (GTD).

What causes choriocarcinoma?

What Causes It? Choriocarcinoma forms when cells that were part of the placenta in a normal pregnancy become cancerous. It can happen after a miscarriage, abortion, ectopic pregnancy, or molar pregnancy — when an egg is fertilized, but the placenta develops into a mass of cysts instead of a fetus.

Who gestational trophoblastic disease classification?

Gestational trophoblastic disease (GTD) can be benign or malignant. Histologically, it is classified into hydatidiform mole, invasive mole (chorioadenoma destruens), choriocarcinoma, placental site trophoblastic tumor (PSTT), and epithelioid trophoblastic tumor (ETT).

What is the most common form of GTD?

Hydatidiform mole (HM) or molar pregnancy is the most common form of GTD. It is most often benign (non-cancerous) and stays in the uterus.

What causes an empty egg?

A blighted ovum, also called an anembryonic pregnancy, occurs when an early embryo never develops or stops developing, is resorbed and leaves an empty gestational sac. The reason this occurs is often unknown, but it may be due to chromosomal abnormalities in the fertilized egg.

What is Hmole?

A hydatidiform mole is growth of an abnormal fertilized egg or an overgrowth of tissue from the placenta. Women appear to be pregnant, but the uterus enlarges much more rapidly than in a normal pregnancy. Most women have severe nausea and vomiting, vaginal bleeding, and very high blood pressure.

How is gestational trophoblastic disease diagnosed?

In addition to a physical examination, the following tests may be used to diagnose GTD:

1. Pelvic examination.
2. Human chorionic gonadotropin (hCG) test.
3. Other lab tests.
4. Ultrasound.
5. X-ray.
6. Computed tomography (CT or CAT) scan.
7. Magnetic resonance imaging (MRI).