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Why was Bumex discontinued?

Why was Bumex discontinued?

Bumetanide was an undisclosed active ingredient in the over-the-counter weight loss supplement StarCaps, which was removed from the market after its presence was discovered by the United States Food and Drug Administration.

Is Bumex or Lasix better for kidneys?

Bumex is the brand name for bumetanide. Compared to Lasix, Bumex is a more potent drug; Bumex is 40 times more potent than Lasix in people with normal kidney function. That means for every 1 mg of Bumex, it would take 40 mg of Lasix to achieve the same effect.

What is Bumex used for?

Bumetanide is used to reduce extra fluid in the body (edema) caused by conditions such as heart failure, liver disease, and kidney disease. This can lessen symptoms such as shortness of breath and swelling in your arms, legs, and abdomen. Bumetanide is a “water pill” (diuretic) that causes you to make more urine.

Is bumetanide stronger than furosemide?

Bumetanide is also a loop diuretic, about 40 times more potent than furosemide. Owing to its high lipid solubility, bumetanide is able to diffuse passively to its site of action, unlike furosemide, which requires active tubular secretion.

Who should not take bumetanide?

Who should not take BUMETANIDE?

  • diabetes.
  • low amount of magnesium in the blood.
  • low amount of calcium in the blood.
  • low amount of potassium in the blood.
  • decreased blood platelets.
  • hearing loss.
  • a coma due to liver failure.
  • liver problems.

Is bumetanide nephrotoxic?

Bumetanide may enhance the nephrotoxicity or ototoxicity of other drugs, particularly in patients with renal impairment. Bumetanide may precipitate encephalopathy in patients with hepatic impairment. Bumetanide may increase uric acid.

What is the most powerful diuretic?

Loop diuretics (furosemide and bumetanide) are the most potent of the diuretics and are widely used in the treatment of pulmonary and systemic edema.

What are the side effects of taking Bumex?

What are the side effects of Bumetanide (Bumex)?

  • hearing problems;
  • confusion, hallucinations, problems with thought or memory;
  • trouble speaking or understanding what is said to you;
  • unusual weakness;
  • twitching, or a seizure;
  • weak or shallow breathing;
  • easy bruising, unusual bleeding, purple or red spots under your skin;

Should I drink lots of water while taking diuretics?

Doctors often recommend drinking less fluid and taking diuretic medications, or water pills, to flush more water and salt out of the body through urine. The goal of treatment is to reduce swelling, which makes it easier to breathe and helps avoid hospitalization.