What are the differences between a transmural MI and an Subendocardial MI?

The transmural type usually consisted of yellowish-brown coagulation necrosis in the center of an infarcted focus and coagulative myocytolysis at the marginal zone. The subendocardial type was characterized by coagulative myocytolysis throughout the entire focus.

What are the differences between a transmural full thickness myocardial infarction MI and a Subendocardial partial thickness MI?

Transmural infarcts involve the whole thickness of myocardium from epicardium to endocardium and are usually characterized by abnormal Q waves on ECG. Nontransmural (including subendocardial) infarcts do not extend through the ventricular wall and cause only ST-segment and T-wave (ST-T) abnormalities.

What is a transmural MI?

A transmural myocardial infarction refers to a myocardial infarction that involves the full thickness of the myocardium. It was one believed that the development of Q waves indicated the infarction was “transmural;” however, autopsy studies failed to confirm this.

What is a Subendocardial MI?

Subendocardial infarction was defined as typical chest apin (greater than 15 minutes), serum enzyme elevation and persistent (greater than 48 hours) new T wave inversion and/or S-T segment depression in the absence of new pathologic Q waves.

What causes a transmural MI?

The most common cause of a myocardial infarction is the rupture of an atherosclerotic plaque on an artery supplying heart muscle. Plaques can become unstable, rupture, and additionally promote the formation of a blood clot that blocks the artery; this can occur in minutes.

What are the different types of MI?

A heart attack is also known as a myocardial infarction. The three types of heart attacks are: ST segment elevation myocardial infarction (STEMI) non-ST segment elevation myocardial infarction (NSTEMI)

What is Subendocardial layer?

[ sŭb′ĕn-dō-kär′dē-əl ] n. The layer of loose connective tissue that joins the endocardium and myocardium.

Can NSTEMI be transmural?

Background: It is the general perception, that ST-elevation myocardial infarction is associated with transmural ischemia while Non-ST elevation myocardial infarction is found in non-transmural subendocardial ischemia. This association, however, derives primarily from post mortem studies.

Where does subendocardial infarction occur?

A subendocardial infarct results in necrosis exclusively inolving the innermost aspect of the myocardium. Usually a subendocardial infarct is the result of a partially occluded epicardial coronary artery (i.e. NSTEMI).