What is Sertoli cell and its function?

What is Sertoli cell and its function?

Sertoli cells are the somatic cells of the testis that are essential for testis formation and spermatogenesis. Sertoli cells facilitate the progression of germ cells to spermatozoa via direct contact and by controlling the environment milieu within the seminiferous tubules.

What is a Spermatogonium cell?

A spermatogonium (plural: spermatogonia) is an undifferentiated male germ cell. Spermatogonia undergo spermatogenesis to form mature spermatozoa in the seminiferous tubules of the testis. These cells are reserve spermatogonial stem cells which do not usually undergo active mitosis.

What are undifferentiated germ cells?

Primordial germ cells (PGCs) differentiate into eggs or spermatozoa in the ovary or testis, respectively. Spermatogonia are basically classified in two types: undifferentiated spermatogonial stem cells and differentiated spermatogonia committed to mitotic proliferation leading to meiosis.

What is the function of Leydig cell?

Leydig cells are interstitial cells located adjacent to the seminiferous tubules in the testes. The best-established function of Leydig cells is to produce the androgen, testosterone, under the pulsatile control of pituitary luteinizing hormone (LH) (9).

What does the spermatogonium produce?

Mitosis ends when a B spermatogonium yields two primary spermatocytes. The diploid number of primary spermatocytes is halved during meiosis. A primary spermatocyte is transformed into two secondary spermatocytes during meiosis I – these cells then in turn are converted into (1N) spermatids during meiosis II.

What is the function of spermatocyte?

The main function of spermatocytes is to divide and produce immature sperm called spermatids.

Why are germ cells haploid?

Each mature germ cell is haploid, meaning that it has a single set of 23 chromosomes containing half the usual amount of DNA and half the usual number of genes. Except for the egg and the sperm, most cells in the human body contain the entire human genome. Also known as a gamete.

Are sperm cells germ cells?

A germ line is the sex cells (eggs and sperm) that are used by sexually reproducing organisms to pass on genes from generation to generation. Egg and sperm cells are called germ cells, in contrast to the other cells of the body that are called somatic cells.

What is Leydig cell Class 12?

The Leydig cells are the interstitial cells which are located adjacent to the seminiferous tubules in the testes. The important function known of the Leydig cells is to produce the androgen and testosterone. The Leydig cells produce testosterone in the presence of the luteinizing hormone (LH).

How do Leydig cells produce testosterone?

The Leydig cells, located in the interstitial compartment of the testis and nestled between the seminiferous tubules, produce testosterone in response to luteinizing hormone (LH), which is produced and secreted by the pituitary gland (1).