What is ovarian hyperstimulation syndrome?
What is ovarian hyperstimulation syndrome?
Ovarian hyperstimulation syndrome is an exaggerated response to excess hormones. It usually occurs in women taking injectable hormone medications to stimulate the development of eggs in the ovaries. Ovarian hyperstimulation syndrome (OHSS) causes the ovaries to swell and become painful.
What is the pathophysiology of OHSS?
Some immune system products are implied in the pathophysiology of OHSS. A number of cytokines are associated with the inflammatory process that takes place during the late follicular maturation, ovulation, corpus luteum function, and embryo implantation [11].
What is the meaning of OHSS in TLE?
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How do you manage OHSS?
For mild to moderate cases of OHSS, treatment usually involves:
- Avoiding vigorous physical activity.
- Increasing oral intake of fluids.
- Using acetaminophen to relieve symptoms.
- Weighing yourself daily.
- Monitoring yourself for any severe symptoms.
Does ovarian hyperstimulation syndrome affect pregnancy?
OHSS symptoms usually appear a few days after ovulation. Symptoms usually resolve within two weeks, unless pregnancy occurs. Pregnant women often continue to have symptoms for 2-3 weeks or more after a positive pregnancy test. The symptoms gradually go away, and the rest of the pregnancy is not affected.
Can OHSS cause miscarriage?
Conclusions: The early OHSS pattern is associated with exogenously administered HCG and a higher risk of preclinical miscarriage, whereas late OHSS may be closely associated with the conception cycles, especially multiple pregnancies, and is more likely to be severe.
Who is at risk for OHSS?
There are many well-known and clearly-documented risk factors for the development of OHSS including: young age, low body mass index (BMI), polycystic ovarian syndrome (PCOS), allergic history, high antral follicle count, high doses of gonadotropins, high or rapidly rising estradiol levels, large numbers of large and …
Does Ohss increase chance of pregnancy?
OHSS in its severe form is potentially fatal. However, OHSS is an indicator of high fertility with an ultimate pregnancy rate of 52.27% in those who develop OHSS. This compares to an average pregnancy rate of 11.5% – 17.6% in the ART population nationally.
Can OHSS cause twins?
From their investigation, the researchers found that although women with early OHSS were more likely to suffer from miscarriage prior to week seven of gestation, women with late OHSS were more likely to have multiple pregnancies such as twins or triplets.