Why do we give amiodarone in cardiac arrest?

Amiodarone is primarily chosen for ACLS as the first-line antiarrhythmic agent for cardiac arrest. This is because it is effective in improving the rate of return of spontaneous circulation (ROSC) and improved ROSC to hospital admission in adults with refractory v-fib or pulseless v-tach.

How do you give amiodarone in cardiac arrest?

In adult patients, amiodarone can be given for VT/VF cardiac arrest via intravenous (IV)/intraosseous (IO) infusion as a 300 mg rapid bolus followed by an additional bolus of 150 mg IV/IO if VT or VF persists.

Do you dilute amiodarone in cardiac arrest?

Amiodarone may be used prior to direct current (DC) cardioversion. Loading dose: The standard recommended dose is 5mg/kg bodyweight given by intravenous infusion over a period of 20 minutes to 2 hours. This should be administered as a dilute solution in 250 ml 5% dextrose.

How do you give amiodarone IV push?

The current dosing recommendation for intravenous amiodarone is to give ≈1000 mg over the first 24 hours. The initial infusion should contain 3 mL of amiodarone injection (150 mg) in 100 mL D5W (concentration of 1.5 mg/mL). One should infuse this 100 mL over 10 minutes (15 mg/min) for a total of 150 mg.

How do you administer amiodarone injection?

Add 3 mL of Amiodarone HCl Injection (150 mg) to 100 mL D5W (concentration = 1.5 mg/mL). Infuse 100 mL over 10 minutes. Followed by Slow: 360 mg over the NEXT 6 hours (1 mg/min).

How do you give amiodarone infusion?

How do you dilute amiodarone?

See section 4.2. Intravenous injection: 150-300 mg (corresponding to 3-6 ml Amiodarone) is diluted with 10-20 ml 5% w/v Glucose Intravenous Infusion.

What is amiodarone Hydrochloride used for?

Amiodarone is used to treat life-threatening heart rhythm problems called ventricular arrhythmias. This medicine is used in patients who have already been treated with other medicines that did not work well.

Why is amiodarone given with dextrose?

When given intravenously, amiodarone should be mixed in a 5% dextrose solution and should be infused with a volumetric pump. If used in high concentrations (>2 mg/ml), it must be delivered through a central vein because it can cause peripheral phlebitis in <3% of patients.